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You may run into an error involving openssl >= 21.1.0 1 versions. The only known workaround will be to downgrade the package in question to a version that is using < 21.1.01. For an example of this, see https://harvardmed.atlassian.net/wiki/spaces/O2/pages/1594262530/Jupyter+on+O2#urllib3-openssl-error .